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Researchers

Archive, discover and apply for access to Canada’s Genome Library

Overview

The PCGL framework will unify Canada’s human genome sequencing efforts and set out a federated data management system that leverages international standards and respects limitations on the jurisdictional and cultural movement of human genetic data.

Researchers can submit de-identified genotypic and phenotypic project data for secure and sustainable data storage in the PCGL framework. PCGL will implement GA4GH standards and international linkages, providing data discovery and access facilitation through a centralized Data Access Committee Office if needed.

Research Portal

The Research Portal is a web-based platform designed for genomic and clinical data discovery. Aimed at researchers seeking specific datasets for their analyses, it offers a user-friendly interface that allows easy exploration of the clinical and -omics data deposited at the PCGL. 

The aggregate datasets view facilitates comprehensive exploration of the entire PCGL dataset. By strongly adhering to GA4GH standards, it aims to make data sharing more efficient and effective, following FAIR principles (Findable, Accessible, Interoperable, and Reusable). 

For example, it implements the Beacon v2 API, ensuring compatibility with other large-scale genomic initiatives, thereby facilitating data discovery and integration across various platforms. It is an invaluable resource for advancing biomedical research and personalized medicine.

Data Access Portal

The PCGL Data Access Compliance Office (PCGL DACO) handles requests from scientists, researchers, and commercial teams for access to PCGL Controlled Data.

Authorization for access to the Pan-Canadian Genome Library controlled data is study based and is reviewed for compliance with PCGL Policies and Guidelines.

The PCGL DACO is the overarching authority to ensure that data from PCGL will only be used by qualified individuals for public health objectives.

Indigenous Data

The PCGL is establishing an Indigenous Genetics Circle (IGC) (including Indigenous Elders, community members, academic professionals, healthcare practitioners, patient partners and international Indigenous genomics experts) whose role is to coordinate between existing and emerging Indigenous genetics research projects  that require Indigenous expertise. 

Working closely with the Silent Genomes Indigenous Rare Disease Diagnosis (SGIRDD) Steering Committee, a key output of the IGC is knowledge translation resources for researchers, clinicians, patients and communities.

Trainees

The Pan-Canadian Genome Library (PCGL) Training Team aims to support researchers in using the PCGL, as well as throughout their careers in genomics – our goal is to build capacity in the Canadian genomics workforce.

Human genomics research is complex. Researchers require knowledge and skills across many disciplines, including biology, informatics, statistics, and ethics. The PCGL Training Team provides relevant and impactful training resources to develop the knowledge and skills to enable human genomics research.

Contact us to join our mailing list to stay aware of PCGL-specific training opportunities.

Live Training Events

Interested in attending in-person or virtual training events?